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June 28, 2004
Launch
of Shimadzu Corporation and AnGes MG Joint Research Project
-To develop a new therapy for refractory dermatosis with nucleic
acid medicines administered via the needleless pressure injector "Shima
JET." - |
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Shimadzu Corporation and AnGes MG, Inc. officially
announce the signing of a joint research agreement to develop
a new therapy for psoriasis. The therapy uses Shimadzu's "
Shima JET" needleless hypodermic pressure injector for
NF B
decoy oligo, a nucleic acid medicine under development by AnGes.
AnGes is currently conducting research into new externally applied
treatments which are expected to contribute to expanding the
application range of the nucleic acid medicine NFB decoy oligo into the field of atopic dermatosis treatments.
A new delivery method has been sought for psoriasis and other
skin diseases, as psoriasis forms a thick silver-white, scaly
layer over the skin that prevents nucleic acid from penetrating
deeply enough to reach the affected tissue.
"Shima JET" is a needleless pressure injector, released
in September 2001 by Shimadzu Corporation for diabetic patients
to use when self-injecting insulin. This injector is less painful
than conventional hypodermic injections, and rarely causes hardening
of the skin.
This needleless injector uses high pressure to inject medicine
directly into the skin through a plastic nozzle. This technique
allows the drug to reach target cells through even thick psoriasis
scale in a very efficient manner. The “Shima JET” injection
method is so promising for drug delivery that AnGes committed
to the research partnership with Shimadzu.
In this joint R&D project, Shimadzu will supply “Shima
JET” injectors while AnGes develops a treatment for psoriasis,
one of the most stubborn skin diseases, by using the injector
to deliver a medication based on AnGes’ proprietary NFB decoy oligo. |
| Company
Profile |
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| SHIMADZU CORPORATION |
| Headquarters: |
1 Nishinokyo-Kuwabara-cho, Nakagyo-ku, Kyoto 604-8511,
Japan |
| President: |
Shigehiko Hattori |
| Foundation: |
September, 1917 |
| Capital: |
16.8 billion yen (as of March, 2004) |
| Number of employees: |
3,072 (as of March, 2004) |
| Sales: |
150 billion yen (for the term ended in March, 2004) |
| Scope of business: |
Production and distribution of analytical, medical,
aviation, and industrial equipment. |
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