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For Investors The Company


Company profile
 
Corporate name : AnGes MG, Inc.
Head office : 4F, Saito Bio-Incubator, 7-7-15, Saito-asagi, Ibaraki, Osaka, 567-0085 Japan
Established : December 17, 1999
President and CEO : Ei Yamada
Capitalization : 9,439million yen(at the end of December 2007)
Issued and outstanding : 117,213shares (at the end of December 2007)
Number of employees : 91 (to be consolidated at the end of December 2007)
Scope of business :
1.  Research, development and manufacturing of HGF genetic medication
2.  Research, development and manufacturing of nucleatic acid drugs (NFB decoy oligo nucleotides)
3.  Research and development of new vectors (HVJ envelope vector) to form the company's business platform


Corporate chronology
 
December 1999 : Founded as MedGene Co., Ltd. in Izumi-city, Osaka for research and development of gene and nucleotide based drugs and reagents for use in functional analyses of genetic medication.
June 2000 : Changed corporate name to MedGene Bioscience Co., Ltd.
August 2000 : Formed partnership with Ishihara Sangyo Kaisha, Ltd. on manufacturing and marketing of HVJ envelope vectors.
January 2001 : Established Ikeda Laboratory in Ikeda-city, Osaka.
January 2001 : Established Tokyo branch in Minato-ku, Tokyo.
January 2001 : Formed partnership with Daiichi Sankyo Co., Ltd. (former Daiichi Pharmaceutical Co., Ltd.) on development of HGF gene based drug in Japan for PAD.
July 2001 : Moved head office to Toyonaka-city, Osaka.
October 2001 : Founded AnGes, Inc. in the state of Maryland for clinical development in the US.
October 2001 : Changed corporate name to AnGes MG, Inc.
April 2002 : Expanded partnership with Daiichi Sankyo Co., Ltd. (former Daiichi Pharmaceutical Co., Ltd.) on development of HGF gene based drug to the US, Europe and Japan, in the fields of PAD and IHD.
June 2002 : Founded AnGes, Euro Ltd. (business development in Europe) in the county of Sussex, UK.
July 2002 : Founded GenomIdea Inc. in Toyonaka-city, Osaka for gene function analyses.
September 2002 : IPO : AnGes MG achieved listing on the Mothers markets of Tokyo Stock Exchange.
February 2003 : Moved head office of AnGes, Euro Ltd. to Surrey, UK.
May 2003 : Formed partnership with Goodman Co., Ltd, to grant exclusive license of NF-κB decoy oligonucleotide for use in intravascular indications.
September 2003 : Transferred HVJ envelope vectors business to GenomIdea, Inc.
September 2004 : Moved head office to Ibaraki-city, Osaka.
September 2004 : Moved head office of GenomIdea Inc. to Ibaraki-city, Osaka.
June 2005 : Formed partnership with Alfresa Pharma Corporation on development and marketing of NF-κB decoy oligonucleotides in the field of atopic dermatitis in Japan.
August 2005 : Formed partnership with Avontec GmbH, with a cross license arrangement, granting NF-κB decoy for psoriasis in Europe, and obtaining STAT-1 decoy for skin and respiratory diseases in Asia.
May 2006 : Formed partnership with Vical, Inc., investing into Vical’s Phase III program of a gene based drug, “Allovectin-7®”, for metastatic melanoma combined with an equity investment and grant of rights in Asia.
December 2006 : Formed partnership with BioMarin Pharmaceutical, Inc. on marketing and distribution of a product approved in the US, “Naglazyme®” (gulsulfase) for treatment of the genetic disease mucopolysaccharidosis VI in Japan.


Office and affiliated subsidiaries
 
Offices  
Headquarters : 4F, Saito Bio-Incubator, 7-7-15, Saito-asagi, Ibaraki, Osaka, 567-0085 Japan
Saito Lab. : 4F, Saito Bio-Incubator, 7-7-15, Saito-asagi, Ibaraki, Osaka, 567-0085 Japan
Tokyo branch : Mita Suzuki Building 5F, 5-20-14, Shiba, Minato-ku,
Tokyo 108-0014
 
Affiliated subsidiaries  
AnGes, Inc. : 22 Firstfield Rd. Suite 150, Gaithersburg, Maryland 20878, USA
  (San Diego Office)
12707 High Bluff Drive, suite 200 San Diego, CA, 92130
AnGes Euro Limited : Suite 106, Airport House, Purley Way, Croydon, Surrey,
CR0 0XZ, UK
GenomIdea Inc. : 4F, Saito Bio-Incubator, 7-7-15, Saito-asagi, Ibaraki, Osaka, 567-0085 Japan


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