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For Investors What's New



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June 30, 2010 : Published Paper Reporting the Results from Collategene Phase III Clinical Trial Performed in Japan Receives the Research Achievement Award of the Asian Society for Vascular Surgery
April 21, 2010 : Medical Journal Publication of Data from "Collategene" Phase III Clinical Study Performed in Japan
December 25, 2009 : Issuance of Notice of Termination of the License Agreement with Transcription Factor Therapeutics, LLC, on NF-κB Decoy
November 24, 2009 : Agreement on SPA with the US FDA for Phase III Clinical Trial for CollategeneTM, a Drug for Ischemic Disease Treatment
November 24, 2009 : Product Patent on Dumbbell-Type (Ribbon-Type) E2F Decoy Oligonucleotide Granted in Japan
--- Covering a Circular Oligonucleotide Sequence ---
October 22, 2009 : Patent on New Decoy Oligonucleotide Granted in Japan
—Covering NF-κB/ets chimera (double) decoy—
September 3, 2009 : AnGes MG Project Adopted by NEDO as Next Generation Strategic Business Program
– Development of Drug-Eluting PTA Balloon Catheter –
August 31, 2009 : Project of AnGes MG Subsidiary GenomIdea Adopted as Strategic Basic Technology Sophistication Supportive Program - R&D of New Method for Biopharmaceuticals Manufacturing Using Technology to Maintain Vacuum -
July 29, 2009 : Medical-Use Patent on NF-κB Decoy Oligonucleotide Granted in Japan - Covering Psoriasis -
July 14, 2009 : AnGes Project Selected by R&D Project for Creation of Regional Innovation -Development of Medical Products Based on Functional Peptides Derived from Plant Regeneration Mechanism-
April 27, 2009 : Joint R&D with Morishita Jintan Co., Ltd. -Development of New Products Based on Functional Peptides with Antimicrobial Activity-
April 23, 2009 : Intellectual Property Report was updated
April 15, 2009 : Substance Patent on Dumbbell-Type (Ribbon-Type) NF-κB Decoy Oligonucleotide Granted in Japan -Covering a Circular Oligonucleotide Sequence-
March 26, 2009 : AnGes Project Adopted to Receive NEDO Support - Development of Novel Disinfectants with Antibacterial Peptides -
March 2, 2009 : AnGes Reached a Broad Agreement with the FDA on the Clinical Trial Designs for Their Phase III Study with Collategene™
February 16, 2009 : Announcement about the progress of Allovectin-7® Phase 3 pivotal trial
February 6, 2009 : AnGes MG continues the collaborations of plasmid HGF for Japan market with Daiichi-Sankyo while the US/Europe marketing rights are returned
February 4, 2009 : Efficacy of NF-κB decoy oligodeoxynucleotides for periodontal disease confirmed in an animal study -An academic paper published in the scientific journal, Antioxidants & Redox Signaling-
February 2, 2009 : GenomIdea, a Subsidiary of AnGes MG, Signs a Licensing Contract for GEN0101
December 26, 2008 : Promotion of the Program Adopted by the Special District for Development of Advanced Medical Care (Super Special District) - GenomIdea Conducts Evaluations for the Formulation and Manufacture of the Active Pharmaceutical Ingredient -
December 10, 2008 : Announcement of New Developments Concerning the Manufacturing of Novel Nucleic-Acid Hybrid Decoy
November 17, 2008 : The Efficacy of NF-κB/Ets Ribbon Type Decoy on Abdominal Aortic Aneurysm Confirmed in Animal Tests - Announcement by Osaka University at the Annual Scientific Sessions 2008 of the American Heart Association (AHA) -
November 12, 2008 : Termination of Joint Development with Alfresa Pharma Corporation
November 12, 2008 : New Direction in the Development of NF-κB Decoy Oligodeoxynucleotide for the Treatment of Atopic Dermatitis in Japan
November 4, 2008 : Joint R&D by Three Companies into the “Drug-Eluting Balloon Catheter” to Prevent Vascular Restenosis: Efficacy Confirmed in Animal Tests - Results Announced at the 11th Annual Meeting of the Japan Society of Embolus Detection and Treatment -
October 28, 2008 : Therapeutic Effects of GEN0101 on Hormone-Refractory Prostate Cancer Confirmed - Announcement of Results of Animal Studies at the 67th Japanese Cancer Association General Meeting-
October 24, 2008 : Amendments of the License Agreement between Meyer Pharmaceuticals LLC and AnGes MG, Inc.
October 23, 2008 : Announcement of Results of Phase IIa Clinical Trials of STAT-1 Decoy Oligodeoxynucleotide on Psoriasis in Europe
October 9, 2008 : GenomIdea, a Subsidiary of AnGes MG Enters into a Basic Agreement Toward the Signing of a Licensing Contract for GEN0101 (HVJ-E)
October 7, 2008 : Letter of Intent for In-licensing of Novel DNA Vaccines for Influenza
October 2, 2008 : New Medical Use Patent Granted in Europe - Covering Severe Diabetic Peripheral Artery Occlusive Diseases -
October 1, 2008 : Substance Patent for a NF-κB Decoy-Oligonucleotide Granted in Japan - Covering AnGes MG’s Decoy Sequence Currently Under Development -
September 30, 2008 : Announcement of Industrial/Academic Four-Party Joint R&D Project on Novel Nucleic Acid Hybrid Decoy for the Treatment of Intractable Inflammatory Diseases
August 6, 2008 : A Medical Use Patent Granted in Europe for Angiogenesis Targeting a New Gene, Endothelial Nitric Oxide Synthase (eNOS)
July 8, 2008 : New Medical-Use Patent for HGF Gene Therapy Granted in USA - Covering Treatment and Prophylaxis of Auditory Dysfunction -
July 2, 2008 : New Medical Use Patent for HGF Granted in Japan - Covering the Treatment of Lymphedema -
July 1, 2008 : Intellectual Property Report was updated
May 26, 2008 : Medical Use Patent for the Combination Use of HGF and PGIS Granted in Europe − Covering Angiogenic Therapy −
May 15, 2008 : New Medical-Use Patent for HGF Gene Granted in Europe - Covering Cardiomyopathy -
April 14, 2008 : AnGes MG, Inc. Launched Naglazyme in Japan
April 7, 2008 : Medical Use Patent on NF-κB Decoy-Oligo Granted in Europe - Covering Its Use for Atopic Dermatitis
March 28, 2008 : AnGes MG, Inc. Receives Approval for Manufacturing and Marketing of Naglazyme
February 25, 2008 : Status Updates of NDA application of Naglazyme for the Treatment of Mucopolysaccharidosis VI
February 12, 2008 : Supplemental Announcement of Results of Phase II Clinical Trials of NF-κB Decoy Oligodeoxinucleotides on Atopic Dermatitis
February 8, 2008 : Announcement of Results of Phase II Clinical Trials of NF-κB Decoy Oligodeoxynucleotide on Atopic Dermatitis
November 15, 2007 : Announcement of a Contract Concluded by Three Companies on R&D of “Drug-Eluting Balloon Catheter” for Prevention of Vascular Restenosis
November 15, 2007 : Announcement of Joint R&D Contract Termination between Goodman Co., Ltd. and AnGes MG, Inc.
November 13, 2007 : AnGes MG, Inc., Signs Licensing Deal with Meyer Pharmaceuticals, LLC - The Development and Marketing of NF-κB Decoy Oligo in North America and Europe-
October 29, 2007 : Academic Release of Data from Phase III Clinical Trial of HGF Gene Therapy Conducted in Japan
August 31, 2007 : A Research-and-Development Project of GenomIdea Inc., a Subsidiary of AnGes MG, Inc. is Granted Subsidy from New Energy and Industrial Technology Development Organization - Development of Cancer Therapeutic Agent Using HVJ-E Vector -
August 29, 2007 : Basic Patent of HGF Gene Therapy is Granted in Korea
August 13, 2007 : AnGes MG, Inc. Submits BLA for Naglazyme in Japan
July 11, 2007 : Basic Patent for HVJ-E Granted in Japan: A Patent Covering HVJ-E Vector (Product Patent)
July 9, 2007 : Completion of Targeted Number of Patient Enrollment in Phase II Clinical Trial of NF-κB Decoy Oligo for the Treatment of Atopic Dermatitis in Japan
July 3, 2007 : Intellectual Property Report was updated
June 20, 2007 : Announcement on Acquisition of First-Class Drug Marketing Business License
June 14, 2007 : Announcement of Results of Phase III Clinical Trials of HGF Gene Therapy in Japan
June 7, 2007 : Announcement Regarding the Official Designation of Naglazyme as an Orphan Drug
February 15, 2007 : Toyobo and GenomIdea Forms Business Alliance - Product Launch of Master Cell Bank for Drug Manufacturing -
February 7, 2007 : New Medical-Use Patent for HGF Gene Granted in Japan - Covering Intractable and Diabetes-related Peripheral Arterial Occlusive Diseases -
January 22, 2007 : AnGes MG, Inc. Announces Marketing and Distribution Agreement with BioMarin Pharmaceutical Inc. for Naglazyme in Japan
January 11, 2007 : The Clinical Trial of HGF Plasmid in Japan has Achieved Necessary
Number of Subject Enrollment for Efficacy Analysis
January 10, 2007 : New Medical-Use Patent for HGF Gene Granted in Japan - Covering Cardiomyopathy -
January 5, 2007 : Vical Initiates Pivotal Phase 3 Trial of Allovectin-7® as First-line Therapy for Metastatic Melanoma
November 13, 2006 : Avontec (Germany) Starts Phase IIa Clinical Trials of AVT-01 - Obtaining Approval for Initiation of Clinical Trials in the Field of Asthma in Europe -
October 31, 2006 : AnGes MG Launches Phase II Clinical Trials of NF-κB Decoy Oligo in the Treatment of Atopic Dermatitis in Japan
October 18, 2006 : Efficacy of Drug Delivery System (DDS) Nanoparticles Supported Nucleic Acid Medicine for Atopic Dermatitis, Developed by Hosokawa Powder Technology Research Institute and AnGes MG, Inc. Confirmed in Animal Experiments
September 7, 2006 : AnGes MG Submitted the Notification of the Clinical Trial Plan for NF-κB Decoy Oligo
- Phase II Clinical Trials of NF-κB Decoy Oligo for the Treatment of Atopic Dermatitis Commences -
June 5, 2006 : AnGes MG, Inc. Announce their Policy for Future Development of HGF Gene Therapy
June 5, 2006 : AnGes MG, Inc. Releases the Results of the US Phase II
Clinical Trial with HGF Gene Plasmid for PAD (Peripheral Arterial Disease)
June 1, 2006 : Completion of Reexamination of the Basic US Patent on NFκB Decoy Oligonucleotide -Decision to Maintain Patent-
May 30, 2006 : AnGes MG, Inc. and Vical Inc. Sign Collaborative R&D Agreement for Allovectin-7® as well as Equity Investment Agreement
May 26, 2006 : Results of Phase I Clinical Trials of NFκB Decoy Oligo
in the Treatment of Atopic Dermatitis
May 24, 2006 : A Japanese Medical-Use Patent is Granted for NFκB Decoy Oligonucleotide
-Covering Treatment for Atopic Dermatitis-
May 23, 2006 : Intellectual Property Report was updated
May 8, 2006 : Results of the US Phase I Clinical Trials with HGF Gene Plasmid for
Ischemic Heart Disease (IHD)
April 3, 2006 : AnGes MG, Inc. Announces Newly Establishing a Position of CIPO
(Chief Intellectual Property Officer)
February 22, 2006 : AnGes MG, Inc. Announced Preliminary Results of the US Phase II Clinical
Trial with HGF Gene Therapy for PAD (Peripheral Arterial Disease)
February 3, 2006 : Termination of Joint Development with Seikagaku Corporation
January 31, 2006 : Medical-Use Patent for HGF Gene Granted in U.S.
- Covering Cardiomyopathy -
November 29, 2005 : AnGes Group Forms Business Alliance with FALCO biosystems
November 22, 2005 : Completion of Trial Subject Enrollment for U.S. Phase I Clinical Trial of HGF Plasmid for Ischemic Heart Disease (IHD)
October 11, 2005 : Osaka University, AOKI and AnGes MG Joint Development Project Launched
- Development of Fully Bioabsorbable Next-generation Magnesium Stent -
October 4, 2005 : Medical -Use Patent for HGF (VEGF) Gene Granted in the U.S.
− Covering Cerebrovascular Disorders −
October 3, 2005 : Hosokawa Powder Technology Research Institute Succeeds in Encapsulating Nucleic Acid Drug Developed by AnGes MG within Drug Delivery System (DDS) Nanoparticles
− Evaluation of “Nucleic Acid DDS Preparation” Technology for Inflammatory Dermatoses Begins −
September 26, 2005 : Domestic Clinical Trial for NFκB Decoy Oligo Launched
− Phase I Clinical Trial in Atopic Dermatitis Commences −
August 15, 2005 : Basic Patent for HVJ-E Is Granted in the U.S. Covering HVJ-E As a Foreign Gene Transferring Vector
(Patent for material, usage/transfection method and preparation process of HVJ-E)
August 10, 2005 : Avontec (Germany) and AnGes MG to form an Alliance
-- Obtained a license of STAT-1 Decoy Oligo in Asi --
August 10, 2005 : Nikko Principal Investments Japan Ltd and AnGes MG Inc to form an alliance in Pharma/Lifesciences area
~ An Alliance Fund has been jointly established, and the first investment just completed to a drug development company ~
August 1, 2005 : Consolidated Financial Report for the 6 months ended June 30, 2005
July 25, 2005 : Pharmaceuticals and Medical Devices Agency Completes Review of Initial IND for NFκB Decoy Oligo
- Phase I Clinical Trial in Atopic Dermatitis Underway -
July 8, 2005 : AnGes MG Forms Business Alliance with Alfresa Pharma Corporation
- Joint Research on Atopic Dermatitis Therapeutic Medicine to Prepare for AnGes MG Establishing its own Sales Network -
June 21, 2005 : Rush University Medical Center /USA and AnGes MG executes License Agreement
- AnGes obtains the exclusive right to develop and sell NFκB Decoy Oligonucleotide as a treatment for Disc Degeneration -
June 13, 2005 : Basic patent of HGF gene therapy is granted in Europe
- Our foundation of HGF gene therapy international development is strengthened. -
June 8, 2005 : AnGes MG Starts to Explore Feasibility of a New DDS Drug with MedGel
- Toward Expanding the Application Range of NFκB Decoy Oligo -
May 24, 2005 : Execution of License Agreement with Vical (USA) related to Non-viral Gene Delivery Technology
--Obtained an exclusive right for HGF gene’s delivery--
April 28, 2005 : GenomIdea Launches Service with Mitsubishi Space Software
- Drug Design Service for Next-Generation Nucleic Acid Medicine “siRNA” -
April 27, 2005 : Completion of Trial Subject Enrollment for the US Phase II Clinical Trial of HGF Plasmid for Peripheral Arterial Disease (PAD)
January 26, 2005 : Launch of Joint Research Project between the University of Tokyo Hospital and AnGes MG
--To develop cutting-edge clinical medicine, including genetic medication and cell remediation medicines--
January 24, 2005 : The Research-and-Development Type Venture Business Consortium That Includes AnGes MG, To Receive Research Grant From New Energy and Industrial Technology Development Organization
--Development of NFκB decoy oligo therapeutic agent for IBD--
December 9, 2004 : AnGes MG Selected by Pharmaceuticals and Medical Devices Agency for Research Grant
--Clinical trials are anticipated using NFκB decoy oligo therapeutic agent for atopic dermatitis--
November 24, 2004 : Phase I clinical trials of HGF plasmid for the treatment of Ischemic Heart Disease (IHD) underway in the United States
-- Clinical trials of HGF plasmid for both peripheral arterial disease (PAD) and IHD --
November 9, 2004 : AnGes MG Joins Hands with ImmunoFrontier
-- Transfer of Patent Rights for Cancer DNA Vaccine --
September 1, 2004 : Announcement: Relocation of Headquarters and Research Center
-- Integration of Headquarters and Research Center to Saito --
July 26, 2004 : GenomIdea's Joint Development with Mitsubishi Space Software Bears Fruit
-- Development of a New Drug Design System for the Next-generation Nucleic acid Medicine "siRNA" Completed --
July 12, 2004 : The U.S. Food and Drug Administration (FDA) has given the go-ahead for a clinical trial investigating AnGes' HGF plasmid for the treatment of ischemic heart disease (IHD). This U.S. study will be the first clinical investigation of HGF plasmid for IHD.
June 30, 2004 : AnGes MG to Join the University of Tokyo (Hospital) Project:"22nd Century Medical Center" (tentative name)
-Establishes joint research program on forefront clinical medicine, including development of genetic medication and cell remediation medicines.-
June 28, 2004 : Launch of Shimadzu Corporation and AnGes MG Joint Research Project
-To develop a new therapy for refractory dermatosis with nucleic acid medicines administered via the needleless pressure injector "Shima JET." -
June 7, 2004 : AnGes MG Forms a Business Alliance with NeoChemir.
Expands treatments of ischemic diseases through introduction of a new carbon dioxide generating wound dressing material
June 1, 2004 : The homepage was renewed.
March 23, 2004 : AnGes MG Seeks Faster New Drug Approval-Applications Via Document Management System
- Infocom to be systems integrator for application submission system -
March 17, 2004 : AnGes MG Expanding Its US Presence
- Licensing activities now in full-swing on the bioventure-rich US West Coast -

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